LAM, of lymphangioleiomyomatosis, is een zeldzame longziekte die vooral vrouwen in de vruchtbare leeftijd treft. Bij mensen met LAM beginnen abnormale spierachtige cellen uit de hand te lopen in bepaalde organen of weefsels, vooral de longen, lymfeklieren en nieren. Na verloop van tijd kunnen deze LAM-cellen het gezonde longweefsel vernietigen Lymphangioleiomyomatosis (LAM) LAM Zeldzame longziekte met abnormale en ongecontroleerde celgroei in bepaalde organen en weefsels, vooral in de longen, lymfeklieren en nieren Lymphangioleiomyomatosis optreedt met een frequentie van minder dan 1 geval per 1 miljoen inwoners en wordt gekenmerkt door abnormale proliferatie van goedaardige gladde spiercellen in de thorax, waaronder het parenchym van de long, lymfe- en bloedvaten en pleura, wat leidt tot een verandering in de long structuren, emfyseem en cystische geleidelijke afname in longfunctie richtlijn Lymphangioleiomyomatosis diagnosis and management; high resolution chest computed tomography, transbronchial lung biopsy and pleural disease management.1,2 Nederlandse aanbeveling op basis van expert opinion: Bij iedere patiënt met LAM moet de diagnose TSC worden overwogen
Lymphangioleiomyomatosis (LAM) is a rare, progressive and systemic disease that typically results in cystic lung destruction. It predominantly affects women, especially during childbearing years. [1] The term sporadic LAM is used for patients with LAM not associated with tuberous sclerosis complex (TSC), while TSC-LAM refers to LAM that is associated with TSC Lymphangioleiomyomatosis (LAM) is an indolent, progressive growth of smooth muscle cells throughout the lungs, pulmonary blood vessels, lymphatics, and pleurae. It is rare and occurs exclusively in young women. Symptoms are dyspnea, cough, chest pain, and hemoptysis; spontaneous pneumothorax is common Lymphangioleiomyomatosis is a multi-system disorder and can affect many organs. Chest. Multiple thin-walled cysts throughout the lungs, usually with a uniform distribution. These are present in nearly all cases. If the cysts are small, they may be seen as diffuse coarse interstitial markings on plain films. general/radiograp Lymphangioleiomyomatosis causes damage to lung tissue that results in such problems as inability of fully oxygenate blood, fluid in the lungs and collapsed lung. Although there is no cure, treatment include drugs that can improve lung function, oxygen therapy and lung transplantation for those with severe disease Category Entertainment; Suggested by AdRev for a 3rd Party Secession Studios; Song Positive and Inspiring Acoustic Rock.wav-Secession Studio
Lymphangioleiomyomatosis (lim-FAN-je-o-LI-o-MI-o-ma-TO-sis), or LAM, is a rare cystic lung disease that mostly affects women in their mid-forties. In LAM, an unusual type of cell begins to grow out of control throughout the body, including in the lungs, lymph nodes and vessels, and kidneys Bekijk in deze symptomenzoeker wat andere zeggen over Lymphangioleiomyomatosis - LAM Samen met slimme zoekalgoritmes kijken waar je klachten vandaan komen! Verzameld voor en door mensen zoals jij en ik Pulmonary lymphangioleiomyomatosis is progressive, and so far there is no cure. Most women with LAM experience a steady decline in lung function, with increased shortness of breath over time
Lymphangioleiomyomatosis (LAM) is a rare progressive multisystem disorder that affects the lungs, the kidneys, and the lymph nodes, found almost exclusively in women of childbearing age, usually in their 30s and 40s. Lymphangioleiomyomatosis can occur in older women as well, although this is less common Pulmonary lymphangioleiomyomatosis: a case of progesterone receptor positive lymphangioleiomyomatosis treated with medroxyprogesterone, oophorectomy and tamoxifen . Br J Dis Chest 1984; 78: 264 -71 How is lymphangioleiomyomatosis (LAM) diagnosed? Because symptoms of lymphangioleiomyomatosis (LAM) are similar to those of asthma or bronchitis, many women who have LAM may not realize it right away, or are given the incorrect diagnosis by doctors who are unfamiliar with the disease.Similarly, the cysts in the lung can be misdiagnosed as emphysema.. Background Lymphangioleiomyomatosis (LAM) is a progressive, cystic lung disease in women; it is associated with inappropriate activation of mammalian target of rapamycin (mTOR) signaling, which reg.. The diagnosis in 2 patients was 'lymphangioleiomyomatosis'; the third patient had anomalies compatible with lymphangioleiomyomatosis, but these were interpreted as tuberous sclerosis because of the presence of renal angiomyolipomas. This disorder occurs exclusively in women in the reproductive age
Since Lymphangioleiomyomatosis is not a disease of lymphatic origin, the etymological origin of the term could be clarified. suggestions? Youni43 18:23, 10 December 2009 (UTC) According to the The British Lung Foundation, LAM mainly affects the lungs, where it causes an overgrowth of a certain type of cell (smooth muscle cell) Ensehede, Netherlands. REFERENCES. 1 Eliasson AH, Phillips YY, Tenholder MF. Lymphangioleiomyomatosis (LAM) is a rare disease of unknown aetiology which mainly affects women of reproductive age Lymphangioleiomyomatosis (LAM) is a rare, progressive and systemic disease that typically results in cystic lung destruction. It predominantly affects women, especially during childbearing years. The term sporadic LAM is used for patients with LAM not associated with tuberous sclerosis complex (TSC), while TSC-LAM refers to LAM that is associated with TSC Johnson SR. Lymphangioleiomyomatosis. Eur Respir J. 2006;27:1056-65. Moses MA, Harper J, Folkman J. Doxycycline treatment for lymphangioleiomyomatosis with urinary monitoring for MMPs. N Engl J Med. 2006;354:2621-2. Johnson SR, Whale CI, Hubbard RB, Lewis SA, Tattersfield AE. Survival and disease progression in UK patients with. Lymphangioleiomyomatosis is one of the rarest lung illnesses that usually affects the women in their child bearing period of life. However, lymphangioleiomyomatosis, also known as LAM, can also affect men but very rarely. Know the causes, symptoms, treatment, prognosis, life expectancy and risk factors of Lymphangioleiomyomatosis
Lymphangioleiomyomatosis (LAM) is a multisystem disease occurring primarily in women that is characterized by lung destruction, renal tumors (angiomyolipomas), and lymphatic involvement. LAM is associated with proliferation of the neoplastic LAM cell, which has mutations/loss of function of the tumor suppressor genes, tuberous sclerosis complex TSC1 or TSC2 lymphangioleiomyomatosis. ICD10-code. D48.1. Verder lezen / Referenties. CJ van Loenhout, MA den Bakker ea, 'Een zeldzame vorm van obstructief longlijden' gepubliceerd in de rubriek 'Casuïstiek' van het Nederlands Tijdschrift voor Geneeskunde van 2017; 161: D757 Lymphangioleiomyomatosis (LAM) Longarts drs. Frouke van Beek en ILD-verpleegkundige Elma Zwanenburg bezochten eind september de Rare Lung Disease Conference 2016, Cincinatti. Een uniek concept waar patiënten, wetenschappers en professionals uit de zorg de nieuwste inzichten en vraag-stukken delen. Zo'n 225 LAM-patiënte lymphangioleiomyomatosis. Proc Natl Acad Sci U S A 2000; 97: 6085-90. 7. Astrinidis A, et al. Mutational analysis of the tuberous sclerosis gene TSC2 in patients with pulmonary lymphangioleiomyomatosis. J Med Genet 2000; 37: 55-57. 8.Johnson SR, et al. European Respiratory Society guidelines for the diagnosis and management of. De Noordzeeziekte: de naam klinkt vrij onschuldig, maar de ziekte heeft een zeer ernstig verloop. Wereldwijd zijn er maar 25 patiënten die deze ziekte hebben. Door schokken in hun lichaam en epileptische aanvallen worden ze steeds minder mobiel. De Noordzeeziekte is één van de meeste zeldzame ziektes ter wereld en het UMC Groningen doet er onderzoek naar. In totaal zijn er wereldwijd zo'n.
Radiological evidence of lymphangioleiomyomatosis in female and male patients with tuberous sclerosis complex Stichting Tubereuze Sclerose Nederland (STSN), Netherlands (2004) Google Scholar. 22. B.A. Zonnenberg, H. Stroink, M.H. Lequin, et al.Leidraad voor de medische begeleiding van kinderen met tubereuze sclerose Nederlands English; Publication. A diagnosis of lymphangioleiomyomatosis in a pregnant woman presenting with a retroperitoneal mass van Loon, AJ., Jul-1999, In : British Journal of Obstetrics & Gynaecology. 106, 7, p. 747-748 2 p. Research output: Contribution to journal › Article › Academic › peer-review Initial presentation of lymphangioleiomyomatosis in third trimester of pregnancy. Coronavirus: The Netherlands. 1 author. 3. Pulmonary Medicine, OLVG, Amsterdam, The Netherlands. BMJ Case Reports, 18 Jan 2021, 14(1) DOI: 10.1136/bcr-2020-237824 PMID: 33462017 . Share this article Share. Moir LM. Lymphangioleiomyomatosis: Current understanding and potential treatments. Pharmacol Ther. 2016 Feb;158:114-24; Johnson SR, Cordier JF, Lazor R, et al; Review Panel of the ERS LAM Task Force. European Respiratory Society guidelines for the diagnosis and management of lymphangioleiomyomatosis. Eur Respir J. 2010 Jan;35(1):14-2 Looking for online definition of Lymphangioleiomyomatosis or what Lymphangioleiomyomatosis stands for? Lymphangioleiomyomatosis is listed in the World's largest and most authoritative dictionary database of abbreviations and acronyms. Lymphangioleiomyomatosis.
Conditions: Lymphangioleiomyomatosis; Tuberous Sclerosis Complex . NCT04388371. Enrolling by invitation. Glutamine PET Imaging in LAM. Conditions: Lymphangioleiomyomatosis (LAM) NCT03193892. Unknown status. A National Registry on Chinese Patients With Lymphangioleiomyomatosis How to say lymphangioleiomyomatosis in English? Pronunciation of lymphangioleiomyomatosis with 3 audio pronunciations, 7 translations and more for lymphangioleiomyomatosis Pulmonary lymphangioleiomyomatosis and cerebrotendinous xanthomatosis: is there a link? Dormans TP(1), Verrips A, Bulten J, Cox N. Author information: (1)Department of Internal Medicine, University Hospital Nijmegen, The Netherlands. A 41-year-old woman had progressive shortness of breath. Cerebrotendinous xanthomatosis was diagnosed 4 years. Netherlands, 3Minnesota Epilepsy Group, St Paul, Minnesota,4Novartis Pharmaceuticals Corporation, East Hanover, lymphangioleiomyomatosis (sLAM) † Identification of blood tests to monitor efficacy of medication in patients at increased risk from the effects of imagin
Request PDF | Acute abdominal pain and fever in a young woman as the first symptoms of lymphangioleiomyomatosis | A previously healthy 28-year-old woman presented to the emergency clinic with. A 41-year-old woman had progressive shortness of breath. Cerebrotendinous xanthomatosis was diagnosed 4 years before. An open-lung biopsy showed the simultaneous presence of cerebrotendinous xanthomatosis and pulmonary lymphangioleiomyomatosis. This is perhaps the first time the coincidental occurrence of these two diseases is described Definition of lymphangioleiomyomatosis in the Definitions.net dictionary. Meaning of lymphangioleiomyomatosis. What does lymphangioleiomyomatosis mean? Information and translations of lymphangioleiomyomatosis in the most comprehensive dictionary definitions resource on the web Dupuytren's disease is a very common condition, affecting 4% of the general UK and US population. It causes the fingers to curl irreversibly into the palm and can be extremely disabling
Lymphangioleiomyomatosis (LAM), a multisystem disease primarily affecting women, is characterized by the proliferation of abnormal-appearing cells (ie, LAM cells) that have a smooth muscle cell phenotype expressing melanoma antigens and are capable of metastasizing, leading to cystic destruction of the lungs, infiltration of the axial lymphatics (eg, lymphangioleiomyomas), and abdominal tumors. Results. Serum VEGF-D levels were greater in patients with LAM compared to those of healthy volunteers (p < 0.001). However, when patient samples were grouped based on the extent of lymphatic extrapulmonary involvement (eg, lymphangioleiomyomas and adenopathy), the statistical difference was maintained only for patients with LAM with lymphatic involvement (p < 0.001), not for those patients. The importance of biobank and nationwide registry for lymphangioleiomyomatosis in a small sized country DSpace/Manakin Repositor Lymphangioleiomyomatosis (LAM) is a rare, cystic lung disease with progressive pulmonary function loss caused by progressively proliferating LAM cells. The degree of airway obstruction has not been well investigated within the pathogenesis of LAM. Using a combination of ex vivo computed tomography (CT), microCT and histology, the site and nature of airway obstruction in LAM explant lungs was.
Lymphangioleiomyomatosis (LAM), a multisystem disease occurring primarily in women, is characterized by cystic lung destruction, and kidney and lymphatic tumors, caused by the proliferation of abnormal-appearing cells (ie, LAM cells) with a smooth muscle cell phenotype that express melanoma antigens and are capable of metastasizing. Estrogen receptors are present in LAM cells, and this finding. Objectives: We examined the long-term effects of everolimus in patients with renal angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis. Methods: Following favorable results from the double-blind core phase of EXIST-2 (NCT00790400), patients were allowed to receive open-label everolimus (extension phase)
Aims: The purpose was to determine the exposure-response relationship of everolimus in patients with angiomyolipoma from the EXIST-2 trial and to analyze the correlation between exposure and plasma concentrations of angiogenic biomarkers in these patients. Methods: One hundred and eighteen patients with angiomyolipoma associated with tuberous sclerosis complex (TSC) or sporadic. A diagnosis of lymphangioleiomyomatosis in a pregnant woman presenting with a retroperitoneal mass. Department of Obstetrics and Gynaecology, University Hospital Groningen, The Netherlands. Correspondence: Dr M. J. N. Weinans, Department of Obstetrics and Gynaecology, University Hospital, Hanzeplein 1, PO Box 30.001,9700 RB Groningen, The.
Lymphangioleiomyomatosis (LAM) Market research report is very much essential in many ways to grow the business and thrive in the market. The market transformations are highlighted here which occur because of the moves of key players and brands like developments, product launches, joint ventures, merges and accusations that in turn changes the view of the global face of Pharmaceutical industry Lymphangioleiomyomatosis (LAM) is a rare idiopathic disease, mainly affecting women of reproductive age, that is characterized by the proliferation of atypical muscle cells (LAM cells) around the airways, blood vessels, and lymphatics, which can result in vascular and airway obstruction and cyst formation (1-4).The main clinical features are progressive dyspnea, pneumothorax, chylothorax.
LAM = Lymphangioleiomyomatosis Looking for general definition of LAM? The LAM means Lymphangioleiomyomatosis. We are proud to list acronym of LAM in the largest database of abbreviations and acronyms. The following image shows one of the definitions of LAM in English: Lymphangioleiomyomatosis This clinical trials features 8 companies, including Tuberous Sclerosis Alliance, AstraZeneca Plc, Nobelpharma Co Ltd, MultiMedica SpA, LAM Therapeutics, C. H. Boehringer Sohn AG & Co K Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM) - Full Text View
Disease(s): Lymphangioleiomyomatosis Intervention(s): albuterol inhaler, albuterol nebulizer, PFT Locations: National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States. Trial of Aromatase Inhibition in Lymphangioleiomyomatosis. Status: Completed. Lymphangioleiomyomatosis (LAM) is a rare lung disease that almost exclusively affects women and develops in about one in 400 000 adult females. The European Lung Foundation worked closely with one of the patient organisations within its network, the European LAM Federation, to raise awareness of LAM at the 2014 European Respiratory Society International Congress in Munich, Germany Clinical Trials on Lymphangioleiomyomatosis. Clinical Trials Registry. ICH GCP Find link is a tool written by Edward Betts.. searching for Lymphangioleiomyomatosis 5 found (39 total) alternate case: lymphangioleiomyomatosis Interstitial lung disease (1,938 words) exact match in snippet view article find links to article airspaces Chronic: Pulmonary langerhans cell histiocytosis, pulmonary lymphangioleiomyomatosis, honeycomb lung caused by IPF or other diseases Ground.
Lymphangioleiomyomatosis Global Clinical Trials Review, H2, 2017 Size and Share Published in 2017-11-30 Available for US$ 2500 at Researchmoz.u De naam komt van benigne verkalkte tumoren die in de hersenschors kunnen ontstaan. In Nederland zijn er ongeveer 2000 patiënten. De genmutaties zijn bekend, TSC1 op chromosoom 9 en TSC2 op chromosoom 16 (OMIM 191100). Deze genen coderen voor de eiwitten hamartin en tuberin, eiwitten die celgroei en differentiatie reguleren Are you looking for disease information or support? Simply type in the name of a disease or condition and Disease InfoSearch will locate quality information from a database of more than 13,000 diseases and thousands of support groups and foundations Lymphangioleiomyomatosis-Pipeline Insight, 2020 Size and Share Published in 2020-02-14 Available for US$ 1500 at Researchmoz.u
DelveInsight s, Lymphangioleiomyomatosis Pipeline Insight, 2020, report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Lymphangioleiomyomatosis pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products Lymphangioleiomyomatosis (LAM), a rare multisystem disorder that affects primarily women of child-bearing age, is characterized by cystic lung destruction, abdominal tumors (eg, angiomyolipomas [AMLs]), and infiltration of the axial lymphatics in the thorax and abdomen (eg, adenopathy and lymphangioleiomyomas). 1 - 5 Cystic lung destruction can result in a decline in lung function, leading. Lymphangioleiomyomatosis (LAM), a disorder of the lung, occurs in 30% to 80% of women with TSC and increases in prevalence with increasing age 5, 11. It is characterized by infiltration of the lungs by smooth muscle‐like cells and pulmonary remodelling that results in diffuse pulmonary cysts Lymphangioleiomyomatosis (LAM) market also provides you with detailed market analysis for patient analysis, prognosis and cures. Prevalence, incidence, mortality, adherence rates are some of the data variables that are available in the report
Lymphangioleiomyomatosis (LAM) Market research report is very much essential in many ways to grow the business and thrive in the market. The market transformations are highlighted here which occur. Sigma-Aldrich offers abstracts and full-text articles by [A W van Milligen de Wit, M N Meilof-Planteydt] The prevalence of Birt-Hogg-Dube syndrome is estimated at 1:200,000, and tuberous sclerosis 1:11,300 -25,000, sporadic lymphangioleiomyomatosis (LAM) affects around 1:125,000 - 500,000 adult women in Europe. Tuberous sclerosis (TS) is present in 1 in 6,000 births. Pulmonary LAM is present in up to 30-40% of adult TS cases The Report Titled on Lymphangioleiomyomatosis (LAM) Market Report-Development Trends, Market Size, Industry Opportunities and Competitive Landscape in 2020 firstly introduced the Lymphangioleiomyomatosis (LAM) Industry basics: The report covers the scope, size, disposition and growth of the industry including the key sensitivities and success factors
Lymphangioleiomyomatosis is a rare disease that affects females of reproductive age. Microscopically, it is characterized by abnormal proliferation of immature smooth muscle-like cells that grow diffusely in the lung. Extrapulmonary manifestations in the mediastinum, peritoneum and pelvic lymph nodes are uncommon. We here describe a patient who initially presented with pulmonary. Dewar was diagnosed with lymphangioleiomyomatosis — also known as LAM — a decade ago. For some years, she continued her job as a social worker and later counseled homeless people
To determine the gender-specific prevalence of pulmonary cysts typical for lymphangioleiomyomatosis (LAM) in adult patients with known tuberous sclerosis complex (TSC). MATERIALS AND METHODS: A retrospective, cross-sectional study in a cohort of 206 adult TSC patients was performed A hemangioma or haemangioma is a usually benign vascular tumor derived from blood vessel cell types. The most common form is infantile hemangioma, known colloquially as a strawberry mark, most commonly seen on the skin at birth or in the first weeks of life.A hemangioma can occur anywhere on the body, but most commonly appears on the face, scalp, chest or back Patients in EXIST-1 had TSC and subependymal giant cell astrocytoma (SEGA), and patients in EXIST-2 had renal angiomyolipoma and a definite diagnosis of TSC or sporadic lymphangioleiomyomatosis. EVE was administered at 4.5 mg/m 2 /day, with adjustment to achieve target trough levels of 5-15 ng/mL in EXIST-1 and at 10 mg/day in EXIST-2
Πώς να το πω lymphangioleiomyomatosis Αγγλικά; Προφορά της lymphangioleiomyomatosis με 3 ήχου προφορές, 7 μεταφράσεις, και περισσότερα για lymphangioleiomyomatosis Lymphangioleiomyomatosis (LAM) is a rare multisystem disorder characterized by cystic lung destruction that primarily affects women of child-bearing age ().Most LAMs are sporadic, but they can also occur due to a genetic condition called tuberous sclerosis complex (TSC) ().LAM predominantly affects the lungs, but can also occur along the axial lymphatic system, including the lymph nodes in the. 356. Background: We evaluated everolimus, an oral mTOR inhibitor, for treating angiomyolipoma (AML) in patients with tuberous sclerosis complex (TSC) or sporadic lymphangioleiomyomatosis (sLAM). Methods: EXIST-2 (NCT00790400) is a prospective, international, randomized, double-blind, placebo-controlled, phase III study.Patients (≥1 AML with longest diameter ≥3 cm) were stratified by (i. US7811776B2 US12/328,727 US32872708A US7811776B2 US 7811776 B2 US7811776 B2 US 7811776B2 US 32872708 A US32872708 A US 32872708A US 7811776 B2 US7811776 B2 US 7811776B2 Authorit OMICS International is currently managing more than 400 Open Access journals with quality peer review and copyediting process. Find the List of Open Access Journals on Medical, Science and Technology. | Lymphangioleiomyomatosis
Empliciti is a medicine for treating multiple myeloma (a cancer of the bone marrow). It is used together with two other medicines (lenalidomide and dexamethasone) and is given to adults who have received at least one previous cancer treatment Radiopaedia is free thanks to our Supporters & Advertisers Become a Gold Supporter, and see no ad
Ghid de pronunţie : Învaţă cum se pronunţă lymphangioleiomyomatosis în Engleză ca un locuitor nativ. Traducere în engleză a cuvântului lymphangioleiomyomatosis The LAM Foundation is the global leader in the fight against lymphangioleiomyomatosis (LAM). We are dedicated to finding safe and effective treatments, and ultimately a cure, for women living with LAM. Your gift is essential to making a difference in their lives Annette Cuylits is lid van Facebook. Word lid van Facebook om met Annette Cuylits en anderen in contact te komen. Facebook geeft mensen de kans om te.. Affiliations. Department of Surgery, Medical Centre Rijnmond Zuid, Groene Hilledijk 315, 3075 EA, Rotterdam, The Netherlands. Eric J. Hazebroek & Peter D. de Rooi (France), Andrew Peacock a (UK), Anton Vonk Noordegraafa (The Netherlands), Maurice Beghetti b (Switzerland), Ardeschir Ghofrani a (Germany), Published on behalf of the European Society of Cardiology
ਉਚਾਰਨ ਰਹਿਨੁਮਾ: lymphangioleiomyomatosis ਦਾ ਅੰਗਰੇਜ਼ੀ ਵਿਚ ਦੇਸੀ ਲਹਿਜ਼ੇ ਵਾਲ਼ਾ ਉਚਾਰਨ ਸਿੱਖੋ। lymphangioleiomyomatosis ਤਰਜਮਾ ਅਤੇ ਆਡੀਓ ਉਚਾਰ MicroRNA-21 is Induced by Rapamycin in a Model of Tuberous Sclerosis (TSC) and Lymphangioleiomyomatosis (LAM) Lymphangioleiomyomatosis (LAM), a multisystem disease of women, is manifest by the proliferation of smooth muscle-like cells in the lung resulting in cystic lung destruction Hệ bạch huyết là một phần của hệ miễn dịch của động vật có xương sống chống lại mầm bệnh, các dị vật và các tế bào biến dạng (ung thư).Ngoài nhiệm vụ bảo vệ cơ thể nó cũng là một phần của hệ tuần hoàn có nhiệm vụ cân bằng thể dịch, hấp thu chất béo. Nó bao gồm bạch huyết, mạch bạch. A pneumothorax is an abnormal collection of air in the pleural space between the lung and the chest wall. Symptoms typically include sudden onset of sharp, one-sided chest pain and shortness of breath. In a minority of cases, a one-way valve is formed by an area of damaged tissue, and the amount of air in the space between chest wall and lungs increases; this is called a tension pneumothorax